Organic Chemistry - Aldehyde & Ketone Protecting Groups | 19.4b Organic Chemistry

Chad provides a brief lesson on the formation of cyclic acetals to serve as a protecting group for aldehydes and ketones which temporarily protects them from reactions with strong nucleophiles. He begins by showing an example of the formation of a cyclic acetal using ethylene glycol including the cyclic acetal formation mechanism. He then shows the reversibility of the reaction via hydrolysis with H3O+. He then provides a specific sample synthesis problem involving the protecting of an aldehyde from a grignard reagent by conversion to a cyclic acetal that demonstrates the usefulness of cyclic acetals as protecting groups. I've created an organic chemistry page that organizes all my videos by chapter - just an easier way for you to watch my YouTube videos. Check it out at https://www.chadsprep.com/chads-organic-chemistry-videos/ If you want all my study guides, quizzes, and practice exams, check out my premium course at https://www.chadsprep.com/organic-chemistry-youtube 00:00 Lesson Introduction 00:44 Formation and Hydrolysis of Cyclic Acetals Using Ethylene Glycol 03:20 Sample Synthesis Involving a Cyclic Acetal as a Protecting Group https://www.chadsprep.com/ #organicchemistry #organicchemistrytutorial #aldehydesandketones