Cell Biology - Cell Biology | DNA Transcription 🧬

Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this molecular biology lecture, Professor Zach Murphy provides a clear and focused breakdown of DNA Transcription, explaining how genetic information is transferred from DNA to RNA—a critical step in gene expression. We begin by outlining the key differences between prokaryotic and eukaryotic transcription, then dive into the step-by-step process of how RNA polymerase synthesizes RNA from a DNA template. You’ll learn how transcription is initiated at promoter regions, the role of transcription factors in eukaryotes, and how the TATA box and RNA polymerase II coordinate transcription initiation. The lecture walks through elongation, as RNA polymerase travels along the DNA template strand synthesizing pre-mRNA in the 5’ to 3’ direction, and concludes with termination, including rho-dependent and rho-independent mechanisms in prokaryotes and polyadenylation signals in eukaryotes. We also cover important post-transcriptional modifications in eukaryotes, including 5’ capping, 3’ polyadenylation, and RNA splicing, all essential for creating a mature mRNA transcript ready for translation. Whether you’re just beginning molecular biology or reviewing for a deeper understanding of gene regulation, this lecture will give you a solid grasp of how genes are transcribed and processed in cells. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media https://www.tiktok.com/@ninjanerdlectures https://www.instagram.com/ninjanerdlectures https://www.facebook.com/ninjanerdlectures https://x.com/ninjanerdsci/ https://www.linkedin.com/company/ninja-nerd/ 💬 Join Our Community Discord: https://discord.gg/3srTG4dngW #ninjanerd #DNATranscription #CellBiology