Cell Biology - Cell Biology | Cell Cycle Regulation

Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this high-yield cell biology lecture, Professor Zach Murphy provides a focused and clinically relevant overview of Cell Cycle Regulation, explaining how cells control progression through the cycle to ensure accurate growth and division. This lecture builds on your understanding of the cell cycle by emphasizing the molecular checkpoints and proteins that maintain genomic integrity. We explore the key regulatory molecules, including cyclins, cyclin-dependent kinases (CDKs), and CDK inhibitors, and how their interactions govern transitions between G1, S, G2, and M phases. Special attention is given to the G1/S and G2/M checkpoints, where the cell assesses DNA integrity before committing to replication or division. The lecture also highlights the roles of critical tumor suppressors like p53 and RB, as well as proto-oncogenes such as cyclin D and CDK4, demonstrating how dysregulation of these pathways can lead to uncontrolled proliferation and cancer. This lecture ties molecular regulation to clinical relevance, making it easier to understand how cell cycle defects contribute to disease and how these pathways are targeted in cancer therapy. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media https://www.tiktok.com/@ninjanerdlectures https://www.instagram.com/ninjanerdlectures https://www.facebook.com/ninjanerdlectures https://x.com/ninjanerdsci/ https://www.linkedin.com/company/ninja-nerd/ 💬 Join Our Community Discord: https://discord.gg/3srTG4dngW #ninjanerd #CellCycleRegulation #CellBiology