Summary

Keywords

7-91j-foundations-of-computational-and-systems-biology-spring-2014 contigs de bruijn graph de novo assembly directed graph eulerian walk genome assembly human genome overlap layout consensus shortest common superstring string graph

Full Transcript

MIT 7.91J Foundations of Computational and Systems Biology, Spring 2014 View the complete course: http://ocw.mit.edu/7-91JS14 Instructor: David Gifford Prof. Gifford talks about two different ways to assemble a genome de novo. The first approach is overlap layout consensus assemblers, as exemplified by string graph assemblers. The second approach is de Bruijn graph-based assemblers. License: Creative Commons BY-NC-SA More information at http://ocw.mit.edu/terms More courses at http://ocw.mit.edu

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